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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
A rational approach to the management of obstructive sleep apnea syndrome
P Vijaya Krishnan1, S Raghunandhan1, R S Anand Kumar1
1Madras ENT Research Foundation, No.1, 1st Cross Street, Off. 2nd Main Road, Raja Annamalaipuram, Chennai, 600 028 Tamil Nadu India.
Abstract:
Snoring & obstructive sleep apnea syndrome (OSAS) is a globally prevalent problem which is on the rise in recent times. The treatment modalities include medical appliances and surgery. It is mandatory to have a rational approach in the management of OSAS, by meticulously analyzing both anatomical and physiological parameters causing the disorder. To define a rational approach for the management of OSAS, by devising a comprehensive protocol with assessment of anatomical level of obstruction by dynamic MRI and physiological factors by Epworth sleepiness scale (ESS) and Polysomnography. A prospective study in 110 patients was conducted over a period of 2 years, at our institute. All patients in the study group were evaluated with dynamic MRI and ESS and Polysomnography. As per the management protocols defined in the study, surgery was advocated in 46 patients (Group 1) with severe compromise in airway, while another group of 64 patients (Group 2) were provided continuous positive airway pressure support (CPAP). Successful outcomes among these 110 patients were analyzed at the end of the study period. A few patients required multimodal therapy which included surgery and CPAP support. Among 46 patients, surgical treatment proved successful in 41 patients in whom AHI reduced from 46.96 to 12.88 (improved by 62%) and ESS improved by almost ten points. Among 64 patients in CPAP group, AHI reduced from 54.2 to 11.3 (improved by 79%) and ESS improved by 11 points in all the patients, but six of them had poor compliance. Five patients among the surgical group had persistence of symptoms. Inferences derived from the above results proved the success of formulating a rational approach in the management of OSAS. Critical analysis of the anatomical and physiological factors inducing obstructive episodes and an appropriate treatment plan is vital, to produce successful outcomes in patients with OSAS. Failure of surgical procedures, are often due to improper case selection. A small group of patients may require multimodal therapy with surgery and CPAP.
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