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Phenobarbital-induced pellagra resulted in death
Esra Pancar Yuksel1, Sedat Sen, Fatma Aydin
1Department of Dermatology and.
Cutaneous and Ocular Toxicology
|February 19, 2014
Summary
Pellagra, a niacin deficiency disease, often presents with skin issues. This case report details a young woman diagnosed with pellagra due to characteristic hand and foot discoloration.
Area of Science:
- Nutritional Biochemistry
- Dermatology
- Internal Medicine
Background:
- Pellagra results from inadequate niacin (vitamin B3) or tryptophan intake.
- The condition manifests with diverse symptoms, including characteristic cutaneous lesions, gastrointestinal disturbances, and neurological deficits.
Observation:
- A case report of a 29-year-old female patient is presented.
- The patient exhibited significant discoloration of the hands and feet.
Findings:
- The observed symptoms, particularly the skin lesions on extremities, led to a diagnosis of pellagra.
- This case highlights the varied clinical presentations of niacin deficiency.
Implications:
- Early recognition of pellagra's cutaneous manifestations is crucial for timely diagnosis and treatment.
- Understanding the spectrum of pellagra symptoms aids in managing nutritional deficiencies.
- This case underscores the importance of considering nutritional deficiencies in patients presenting with unexplained skin conditions.
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