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CT-guided core biopsy and percutaneous fiducial seed placement in the lung: can these procedures be combined without
Mishal Mendiratta-Lala1, Robert Sheiman2, Olga R Brook2
1Henry Ford Hospital, Department of Radiology, Abdominal Interventional Radiology, 2799 West Grand Blvd, Detroit, MI 48202, United States.
European Journal of Radiology
|February 19, 2014
Summary
Concomitant CT-guided lung biopsy and fiducial seed placement is safe and effective. This combined procedure in select patients does not increase major complications or decrease success rates compared to separate procedures.
Area of Science:
- Interventional Pulmonology
- Thoracic Oncology
- Medical Imaging
Background:
- Percutaneous transthoracic needle biopsy (PTNB) is crucial for diagnosing lung lesions.
- Fiducial marker placement is essential for guiding stereotactic radiotherapy.
- Performing these procedures separately may increase patient burden and resource utilization.
Purpose of the Study:
- To evaluate the safety and efficacy of combining CT-guided core biopsy and fiducial seed placement in the lung.
- To compare complication rates and success rates of the combined procedure versus individual procedures.
Main Methods:
- Retrospective analysis of 285 patients undergoing CT-guided procedures.
- Patients were categorized into three groups: fiducial seed placement alone, core biopsy alone, or combined procedure.
- Comparison of demographics, lesion characteristics, procedural details, and complication rates.
Main Results:
- Major complication rates were similar across all three groups (fiducial alone, biopsy alone, combined).
- Technical success rates were comparable between the groups.
- No significant increase in major complications (pneumothorax, hemothorax) was observed with the combined approach.
Conclusions:
- Combined percutaneous pulmonary core biopsy and fiducial seed placement is a safe and effective strategy.
- The combined procedure can be performed without an increased risk of major complications compared to separate interventions.

