Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of Hemostasis01:24

Disorders of Hemostasis

2.7K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.7K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

2.6K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.6K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

482
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
482
Structure and Function of Platelets01:18

Structure and Function of Platelets

7.1K
The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
7.1K
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

13.0K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
13.0K
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

415
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
415

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Day Surgery in Older Adults: Safety, Effectiveness, and Best Practices for Patient Selection and Perioperative Care-A Narrative Review.

Geriatrics (Basel, Switzerland)·2026
Same author

Functional fibrinolysis in older adults: clinical relevance and implications for personalised anticoagulation.

GeroScience·2026
Same author

Management of Chronic Pain in Elderly Patients: The Central Role of Nurses in Multidisciplinary Care.

Geriatrics (Basel, Switzerland)·2025
Same author

[Artificial intelligence in health education: blessing or curse?]

Orvosi hetilap·2024
Same author

Assays for Monitoring Apixaban and Rivaroxaban in Emergency Settings, State-of-the-Art Routine Analysis, and Volumetric Absorptive Microsamples Deliver Discordant Results.

Diagnostics (Basel, Switzerland)·2024
Same author

Treatment of type 2 diabetes mellitus in the elderly - Special considerations.

Physiology international·2024

Related Experiment Video

Updated: May 3, 2026

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
09:46

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells

Published on: December 27, 2017

19.4K

[Thrombocytopenia].

Klára Gadó1, Gyula Domján1

  • 1Semmelweis Egyetem, Általános Orvostudományi Kar I. Belgyógyászati Klinika Budapest Korányi S. u. 2/A 1083.

Orvosi Hetilap
|February 19, 2014
PubMed
Summary
This summary is machine-generated.

Thrombocytopenia, or low platelet count, is a common cause of bleeding disorders. Identifying the underlying cause is crucial for effective treatment, which may include platelet transfusions but can be contraindicated in certain conditions.

Keywords:
bleeding disordersbone marrowcsontvelőgestation thrombocytopeniaimmune-thrombocytopeniaimmunthrombocytopeniaplateletterhességi thrombocytopeniathrombocytopeniavérzékenység

More Related Videos

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K
Ferric Chloride-induced Murine Thrombosis Models
10:37

Ferric Chloride-induced Murine Thrombosis Models

Published on: September 5, 2016

21.9K

Related Experiment Videos

Last Updated: May 3, 2026

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
09:46

Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells

Published on: December 27, 2017

19.4K
Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K
Ferric Chloride-induced Murine Thrombosis Models
10:37

Ferric Chloride-induced Murine Thrombosis Models

Published on: September 5, 2016

21.9K

Area of Science:

  • Hematology
  • Internal Medicine

Context:

  • Thrombocytopenia is a frequent cause of bleeding abnormalities.
  • Clinical findings include petechias, purpuras, and mucosal bleeding.
  • Severe bleeding, such as gastrointestinal or intracranial hemorrhage, can be life-threatening.

Purpose:

  • To summarize the causes, diagnosis, and management of thrombocytopenia.
  • To highlight the importance of identifying the underlying etiology.
  • To discuss the role and contraindications of platelet transfusion.

Summary:

  • Thrombocytopenia, characterized by a low platelet count, leads to bleeding abnormalities.
  • Diagnostic findings include prolonged bleeding time, with bone marrow and peripheral blood smear examinations being crucial.
  • Therapeutic strategies involve treating the underlying cause and considering platelet transfusion, with careful consideration of contraindications in cases of increased platelet activation.

Impact:

  • Provides a concise overview of thrombocytopenia for clinicians and researchers.
  • Emphasizes the diagnostic and therapeutic challenges.
  • Informs treatment decisions, particularly regarding platelet transfusions.