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Updated: Sep 25, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Published on: January 10, 2015
Anionic porphyrin as a new powerful cell death inducer of Tobacco Bright Yellow-2 cells
C Riou1, C A Calliste, A Da Silva
1Université de Limoges, Laboratoire de Chimie des Substances Naturelles, EA 1069, 123 avenue Albert Thomas, 87060 Limoges, France. stephanie.lhez@unilim.fr.
Abstract:
For the first time, the behaviour of tobacco cell suspensions submitted to four porphyrins was described. The potential killer effect of these photosensitizers on tobacco cells was evaluated. Biological results were correlated with photophysical properties and the reactive oxygen species production capacity of tested compounds. Surprisingly, the anionic free-base porphyrin showed the strongest phototoxic effect.

