Related Experiment Video
Updated: May 3, 2026
03:23
Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
1.6K
Eosinophilic ascites with marked peripheral eosinophilia: a diagnostic challenge
Jessie A Elliott1, Orla McCormack, Nairi Tchrakian
1aDepartment of Surgery, Trinity Centre, St James's Hospital and Trinity College bDepartment of Pathology cDepartment of Immunology dDepartment of Gastroenterology, St James's Hospital, Dublin, Ireland.
European Journal of Gastroenterology & Hepatology
|February 19, 2014
Summary
Eosinophilic gastroenteritis (EGE) is a rare gastrointestinal disorder. This case highlights EGE presenting with eosinophilic ascites, successfully treated with corticosteroids and dietary changes.
Area of Science:
- Gastroenterology
- Immunology
- Allergy
Background:
- Eosinophilic gastroenteritis (EGE) is a rare condition characterized by eosinophilic infiltration of the gastrointestinal tract.
- Clinical presentation varies based on location and depth of infiltration.
- Eosinophilic ascites is an uncommon manifestation of EGE.
Observation:
- A 41-year-old woman with atopy presented with severe abdominal pain and diarrhea.
- Investigations revealed eosinophil-rich ascites, elevated peripheral eosinophil count, and immunoglobulin E levels.
- Bone marrow, vasculitic, and parasitic evaluations were negative for other causes.
Findings:
- Gastrointestinal biopsies confirmed EGE with eosinophilic ascites.
- The patient showed a significant response to systemic corticosteroids and dietary allergen elimination.
Implications:
- This case underscores the diverse presentations of EGE, including eosinophilic ascites.
- Highlights the importance of considering EGE in patients with unexplained ascites and eosinophilia.
- Emphasizes the efficacy of corticosteroids and dietary interventions in managing EGE.
Related Concept Videos
01:19Ascites
47
DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...
47
01:24Nephrotic Syndrome I : Introduction
1.2K
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
1.2K
01:25Pleural Effusion I: Introduction
6.3K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
6.3K
01:26Nephrotic Syndrome II : Assessment and Medical Management
409
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
409