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An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
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Sciatic nerve schwannoma: case report.

Umit Eroglu1, Melih Bozkurt, Ozgur Ozates

  • 1Ankara University, Faculty of Medicine, Department of Neurosurgery, Ankara, Turkey.

Turkish Neurosurgery
|February 19, 2014
PubMed
Summary

Schwannomas, benign nerve sheath tumors, can rarely occur outside the skull. This case highlights a large sciatic nerve schwannoma presenting as chronic sciatica in an adult.

Area of Science:

  • Neurosurgery
  • Oncology
  • Pathology

Background:

  • Schwannomas are benign peripheral nerve sheath tumors, typically occurring in adults aged 20-50.
  • Extracranial schwannomas are rare, with symptoms often mimicking other conditions like herniated discs.
  • The sciatic nerve is a common site for peripheral nerve tumors, though large masses are infrequent.

Observation:

  • A 40-year-old woman presented with a slow-growing mass in her right posterior thigh.
  • Magnetic resonance imaging (MRI) revealed a large mass involving the mid-portion of the right sciatic nerve.
  • The patient experienced chronic sciatica, a common symptom associated with sciatic nerve compression.

Findings:

  • Surgical excision of the mass was performed.
  • Histopathological examination confirmed the diagnosis of schwannoma.

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  • No neurological deficits were observed post-operatively, indicating successful tumor removal.
  • Implications:

    • This case underscores the importance of considering schwannoma in the differential diagnosis of sciatica, especially with a palpable mass.
    • Early diagnosis and surgical intervention can lead to favorable outcomes for patients with sciatic nerve schwannomas.
    • Further research into the management of extracranial schwannomas is warranted to improve patient care.