Related Experiment Videos
Identification of a neutralizing epitope shared by bluetongue virus serotypes 2 and 13
S Ristow1, L Leendersten, J Gorham
1Department of Veterinary Microbiology and Immunology, University of California, Davis 95616.
Journal of Virology
|July 1, 1988
Abstract:
The serotypes of bluetongue virus (BTV) are classified by differences in neutralization commonly induced by P2, a major surface protein. A BTV serotype 13 (BTV-13) monoclonal antibody, 4B13-207A, immunoprecipitated P2s of BTV-13 and BTV-2 and also neutralized both viruses. These data indicate that P2s from BTV-13 and BTV-2 share a common neutralizing epitope that is not detected by neutralizing polyclonal antibody to BTV-13.