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Outcome of preterm infants who suffered neonatal apnoeic attacks

G A Levitt1, A Mushin, S Bellman

  • 1Queen Charlotte's Maternity Hospital, London, U.K.

Insights

Neonatal apnea, a common issue in premature infants, may not lead to poor developmental outcomes if the infant has no other serious health problems. This study followed infants born before 31 weeks post-menstrual age to assess long-term effects.

Area of Science:

  • Neonatology
  • Developmental Pediatrics
  • Pediatric Neurology

Background:

  • Neonatal apnea is a frequent concern in preterm infants, particularly those born at less than 31 weeks post-menstrual age.
  • Previous studies have suggested a poor prognosis associated with neonatal apnea.

Purpose of the Study:

  • To investigate the long-term developmental outcomes of infants born prematurely who experienced neonatal apnea.
  • To determine if neonatal apnea, in the absence of other significant neonatal issues, impacts developmental quotients, sensorineural hearing, or retinopathy.

Main Methods:

  • Thirty infants born before 31 weeks post-menstrual age were monitored for apnea using pneumocardiograms.
  • Follow-up assessments between 16 and 36 months included physical, ophthalmological, audiometry, and developmental evaluations (Griffiths scales).

Main Results:

  • Twenty-five infants experienced apneic attacks.
  • Only two infants with a history of apnea showed an abnormal developmental quotient.
  • No cases of sensorineural deafness or retinopathy of prematurity were detected in infants with apnea.

Conclusions:

  • The generally poor prognosis linked to neonatal apnea may not be applicable to preterm infants who do not have other serious neonatal complications.
  • Early apnea episodes in preterm infants, without concurrent health problems, may not predict adverse long-term neurodevelopmental or sensory outcomes.

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