Related Experiment Video

Updated: May 3, 2026

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
08:48

In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

Published on: November 5, 2021

2.4K

Activity of certain 6-methoxy-8-aminoquinolines against Trypanosoma cruzi

F C GOBLE

    Antibiotics & Chemotherapy (Northfield, Ill.)
    |February 19, 2014
    PubMed
    Abstract

    No abstract available in PubMed .

    Keywords:
    QUINOLINES/effectsTRYPANOSOMIASIS/experimental

    More Related Videos

    Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System
    06:13

    Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System

    Published on: July 31, 2019

    8.1K
    Establishment of Larval Zebrafish as an Animal Model to Investigate Trypanosoma cruzi Motility In Vivo
    13:21

    Establishment of Larval Zebrafish as an Animal Model to Investigate Trypanosoma cruzi Motility In Vivo

    Published on: September 30, 2017

    13.4K

    Related Experiment Videos

    Last Updated: May 3, 2026

    In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
    08:48

    In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase

    Published on: November 5, 2021

    2.4K
    Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System
    06:13

    Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System

    Published on: July 31, 2019

    8.1K
    Establishment of Larval Zebrafish as an Animal Model to Investigate Trypanosoma cruzi Motility In Vivo
    13:21

    Establishment of Larval Zebrafish as an Animal Model to Investigate Trypanosoma cruzi Motility In Vivo

    Published on: September 30, 2017

    13.4K

    Related Concept Videos

    Anthelminthic Agents01:15

    Anthelminthic Agents

    103
    Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
    103
    Inhibitors of Bacterial DNA Synthesis01:28

    Inhibitors of Bacterial DNA Synthesis

    130
    Bacterial pathogens depend on precise and efficient DNA replication to sustain infection. Two type II topoisomerases—DNA gyrase and topoisomerase IV—are critical to this process, as they resolve DNA supercoiling and unlink chromosomes during replication. Fluoroquinolones, synthetic derivatives of quinolones, exploit this mechanism by stabilizing the transient DNA–enzyme cleavage complex, preventing strand religation, and causing lethal double-strand breaks. These...
    130

    Articles linked to this work by shared authors, journal, and citation graph.

    Factors influencing the development of melatonin rhythmicity in humans.

    The Journal of clinical endocrinology and metabolism·1996

    Development of melatonin production in infants and the impact of prematurity.

    The Journal of clinical endocrinology and metabolism·1992

    Pharmacovigilance in the treatment of cutaneous leishmaniasis: adverse event profile at a reference center.

    Revista da Sociedade Brasileira de Medicina Tropical·2026

    Total synthesis as a critical tool for structural revision of natural products.

    Chemical communications (Cambridge, England)·2026

    Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review).

    Molecular medicine reports·2026

    Disproportionate reporting of seizures with histamine H1 receptor antagonists: The role of drug generation and brain H1 receptor occupancy assessed using the Japanese Adverse Drug Event Report database.

    International journal of clinical pharmacology and therapeutics·2026

    Discovery of tricyclic benzo[4,5]imidazo[2,1-b]thiazole-3-hydroxyindolin-2-one hybrids as selective MAO-B and cholinesterase inhibitors.

    RSC advances·2026

    Simultaneous exploitation of phaeanthine - a bisbenzylisoquinoline alkaloid for dual anti-metastatic and anti-angiogenic potential by disruption of Akt/NF-κB/MMP regulatory pathways.

    RSC medicinal chemistry·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us