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Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria
Published on: February 28, 2025
New flavonoids C-glycosides from Rhabdophyllum arnoldianum
Joséphine Ngo Mbing1, Marius Balemaken Missi, Joseph Thierry Ndongo
1a Department of Organic Chemistry , Faculty of Science, University of Yaoundé I , P.O. Box 812, Yaoundé , Cameroon.
Abstract:
Two new flavone glycosides, 3″-O-acetyl-7-O-methylvitexin (1) and 6″-α-rhamnopyranosyl-7-O-methylvitexin (2), along with nine known compounds (3-11) were isolated from the leaves of Rhabdophyllum arnoldianum (Ochnaceae). The structures of the new compounds were established by detailed spectroscopic studies and mass spectrometry, while known compounds were characterised by direct comparison of their reported NMR data with those found in the literature. All these compounds were the first reported from Rhabdophyllum genus. The biological assays on crude extracts and compounds of this plant demonstrated that the crude extracts possess significant antimicrobial activity against Gram-positive bacteria.

