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Updated: May 2, 2026

Advancing High-Resolution Imaging of Virus Assemblies in Liquid and Ice
Published on: July 20, 2022
In situ cryogenic transmission electron microscopy for characterizing the evolution of solidifying water ice in
Kaiping Tai1, Yin Liu1, Shen J Dillon1
1Department of Materials Science and Engineering, University of Illinois Urbana-Champaign, IL 61801, USA.
Abstract:
The details of ice interface dynamics in complex systems are critical to a variety of natural and commercial processes. A platform for low temperature environmental transmission electron microscopy is developed and applied to characterization of ice crystallization in colloidal solutions. The platform is utilized for studying the phase evolution in ice during crystallization and the dynamic interactions of Au nanoparticles at the crystallization front. The results indicate that models developed to treat ice-particle interactions at the micron scale extend well to the nanoscale.
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