Related Experiment Video
Updated: May 2, 2026
12:31
A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
17.1K
In vitro selection of RNA aptamers for a small-molecule dye
1The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Japan.
Methods in Molecular Biology (Clifton, N.J.)
|February 20, 2014
Abstract:
Artificial riboswitches can be generated by functional coupling of an RNA aptamer for synthetic small molecule to an expression platform. RNA aptamers that can bind strongly and selectively to their target are feasible to be used for obtaining more potent artificial riboswitches. In this chapter, we describe tips and notes for in vitro selection of RNA aptamers targeting synthetic small molecules.
