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Hyperglycemia in critically ill children
Vinayak Krishnarao Patki1, Swati Balasaheb Chougule2
1Department of Pediatrics, Wanless Hospital Miraj, India.
Summary
High blood sugar (hyperglycemia) is common in critically ill children and significantly increases their risk of death and complications. This study highlights the critical link between hyperglycemia and poor outcomes in pediatric intensive care.
Area of Science:
- Pediatric critical care medicine
- Endocrinology
- Clinical research
Background:
- Hyperglycemia is a common metabolic derangement in critically ill patients.
- The impact of hyperglycemia on outcomes in critically ill children requires further investigation.
Purpose of the Study:
- To determine the incidence of hyperglycemia in critically ill children.
- To investigate the association between hyperglycemia and clinical outcomes, including morbidity and mortality.
Main Methods:
- Prospective observational study in a pediatric intensive care unit (PICU).
- 101 non-diabetic children (1 month-16 years) monitored for blood glucose levels.
- Hyperglycemia defined as blood glucose >126 mg/dl; outcomes compared between hyperglycemic and non-hyperglycemic groups.
Main Results:
- Hyperglycemia incidence was high at 69.3% in critically ill children.
- Hyperglycemic children showed significantly higher rates of mechanical ventilation, inotropic support, longer PICU stays, and mortality (28.6% vs. 3.2%).
- Peak blood glucose and duration of hyperglycemia were independently associated with increased mortality risk.
Conclusions:
- Hyperglycemia is prevalent in critically ill children.
- Hyperglycemia is significantly associated with increased morbidity and mortality in this population.
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