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Published on: March 6, 2018
Influence of bottle-feeding on serum bisphenol a levels in infants
Young-Jun Rhie1, Hyo-Kyoung Nam1, Yeon Joung Oh2
1Department of Pediatrics, Korea University College of Medicine, Seoul, Korea.
Insights
Bottle-feeding significantly increases infant exposure to Bisphenol A (BPA), an endocrine disrupting chemical found in plastics. Health policies are needed to reduce this widespread BPA exposure in babies.
Area of Science:
- Environmental Health
- Pediatric Health
- Toxicology
Background:
- Endocrine disrupting chemicals (EDCs) pose risks, especially during development.
- Bisphenol A (BPA) is a prevalent EDC found in common plastic products.
- Infant exposure to BPA is a growing public health concern.
Purpose of the Study:
- To investigate infant exposure to Bisphenol A (BPA).
- To determine the effect of bottle-feeding on serum BPA levels in infants.
- To assess potential correlations between BPA levels and infant demographics.
Main Methods:
- Serum BPA levels were measured in 60 healthy infants aged 6-15 months using competitive ELISA.
- Infants were categorized into bottle-fed and breast-fed groups.
- Statistical analysis compared BPA levels between groups and correlated them with age, weight, and gestational age.
Main Results:
- BPA was detected in all infant serum samples.
- Bottle-fed infants exhibited significantly higher serum BPA levels (96.58±102.36 pg/mL) compared to breast-fed infants (45.53±34.05 pg/mL).
- No significant differences in BPA levels were observed between genders, nor correlations with age, weight, or gestational age.
Conclusions:
- Bottle-feeding is associated with increased infant exposure to BPA.
- Urgent establishment of health policies is recommended to mitigate BPA exposure in infants.
- Reducing BPA in products used by infants is crucial for protecting developmental health.
Abstract:
Exposure to endocrine disrupting chemicals (EDCs), particularly during developmental periods, gives rise to a variety of adverse health outcomes. Bisphenol A (BPA) is a well-known EDC commonly found in plastic products including food and water containers, baby bottles, and metal can linings. This study investigates infant exposure to BPA and the effect of bottle-feeding on serum BPA levels in infants. Serum BPA levels in normal healthy infants 6 to 15 months of age (n=60) were evaluated by a competitive ELISA. BPA was detected in every study sample. Serum BPA levels of bottle-fed infants (n=30) were significantly higher than those of breast-fed infants (n=30) (96.58±102.36 vs 45.53±34.05 pg/mL, P=0.014). There were no significant differences in serum BPA levels between boys (n=31) and girls (n=29). No significant correlations were found between serum BPA levels and age, body weight, birth weight, and gestational age. Bottle-feeding seems to increase the risk of infant exposure to BPA. Establishment of health policies to reduce or prevent BPA exposure in infants is necessary.
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