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Updated: May 2, 2026

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
A case of endobronchial polyp mimicking congenital lobar emphysema in an infant
Rahele Mehrain1, Abbas Hadipur2
1Non-Communicable Pediatric Diseases Research Center, Amirkola Hospital , Babol University of Medical Sciences, Babol , Iran. ; Department of Radiology, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran.
Insights
Congenital lobar emphysema in infants can be mimicked by an endobronchial polyp. Bronchoscopy is crucial for accurate diagnosis before surgical intervention for suspected infantile lobar emphysema.
Area of Science:
- Pediatric Respiratory Medicine
- Thoracic Surgery
Background:
- Congenital lobar emphysema (CLE) is a rare infant respiratory disease characterized by air trapping due to cartilage deficiency and bronchomalacia.
- CLE presents with respiratory distress, often diagnosed via imaging suggesting lung hyperinflation.
Observation:
- An 18-month-old infant presented with acute respiratory distress.
- Chest X-ray revealed findings consistent with CLE, including unilateral lung lucency and mediastinal shift.
- Bronchoscopy identified an endobronchial polyp in the left lower bronchus.
Findings:
- Biopsy confirmed the lesion as an endobronchial polyp.
- The polyp successfully mimicked the radiographic and clinical presentation of congenital lobar emphysema.
- This case highlights a rare differential diagnosis for infantile lobar emphysema.
Implications:
- Emphasizes the diagnostic importance of bronchoscopy in infants with suspected CLE.
- Suggests considering endobronchial polyps as a differential diagnosis for infantile lobar emphysema.
- Highlights the potential for less invasive procedures to avoid unnecessary lobectomy.
Background:
Congenital lobar emphysema, also called infantile lobar emphysema, is a respiratory disease that occurs in infants when air enters the lungs and cannot leave easily. It results from cartilage deficiency and bronchomalacia causing distal air trapping and respiratory distress. In this study, we present a case of endobronchial polyp mimicking congenital lobar emphysema.
Case Presentation:
An 18-month old infant was admitted to the hospital due to sudden respiratory distress. Chest x- ray showed left hemithorax lucency, mediastinal shift to the right side, left hemidiaphragm flattening, and left oblique fissure bulging to the superior. A broncoscopy showed polyp in the left lower bronchus and the biopsy of the lesion confirmed to be the polyp.
Conclusion:
The findings of this case emphasize the value of bronchoscopy prior to lobectomy in cases of congenital lobar emphysema.
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