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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Clinical Applications of Epidermal Stem Cells01:19

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Related Experiment Video

Updated: May 2, 2026

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells
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Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

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Eccrine porocarcinoma: a case report.

Sharathkumar H K1, Hemalatha A L2, Deepthi B Ramesh3

  • 1Associate Professor, Department of Pathology, Mysore Medical College and Research Institute , Mysore, India .

Journal of Clinical and Diagnostic Research : JCDR
|February 20, 2014
PubMed
Summary

Eccrine porocarcinoma, a rare sweat gland cancer, typically affects the elderly and extremities. Early diagnosis and treatment are crucial due to its aggressive nature and metastatic potential.

Keywords:
Eccrine porocarcinomaMalignantSweat gland tumour

Related Experiment Videos

Last Updated: May 2, 2026

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08:17

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

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Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Eccrine porocarcinoma is an exceptionally rare malignancy originating from eccrine sweat glands.
  • It can arise independently (de novo) or from a pre-existing eccrine poroma.
  • This cancer predominantly affects elderly individuals, with a mean age of 67, and commonly presents on the extremities, especially the legs and feet.

Purpose of the Study:

  • To highlight the aggressive clinical behavior and metastatic potential of eccrine porocarcinoma.
  • To emphasize the importance of early diagnosis and prompt treatment for this rare malignancy.
  • To present a case study of eccrine porocarcinoma in a 55-year-old female, given its rarity.

Main Methods:

  • Case report presentation.
  • Review of clinical presentation and histopathological findings.
  • Discussion of diagnostic and therapeutic challenges associated with eccrine porocarcinoma.

Main Results:

  • Eccrine porocarcinoma exhibits a propensity for multiple cutaneous and visceral metastases.
  • The tumor's aggressive behavior necessitates vigilant monitoring and timely intervention.
  • The presented case involves a 55-year-old female patient with eccrine porocarcinoma.

Conclusions:

  • Eccrine porocarcinoma is a rare but aggressive neoplasm requiring prompt diagnosis and management.
  • Metastatic potential, including both cutaneous and visceral sites, is a significant concern.
  • Further research and case reporting are vital for understanding and combating this rare cancer.