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Published on: February 26, 2013
Heavy alcohol consumption and risk of atrial fibrillation. The Circulatory Risk in Communities Study (CIRCS)
Fumihiko Sano1, Tetsuya Ohira, Akihiko Kitamura
1Public Health, Department of Social and Environmental Medicine, Osaka University, Graduate School of Medicine.
Insights
Heavy alcohol consumption significantly increases the risk of atrial fibrillation (AF) in Asian populations. This study highlights the importance of monitoring alcohol intake to prevent AF incidence.
Area of Science:
- Cardiology
- Epidemiology
- Public Health
Background:
- Limited data exists on alcohol consumption and atrial fibrillation (AF) risk in Asian populations.
- Understanding this relationship is crucial for public health initiatives and preventative strategies.
Purpose of the Study:
- To investigate the association between varying levels of alcohol consumption and the incidence of AF.
- To provide evidence specific to a Japanese population cohort.
Main Methods:
- A population-based cohort study (Circulatory Risk in Communities Study - CIRCS) involving 8,602 Japanese adults.
- Data collected on weekly alcohol intake, with AF incidence ascertained through ECGs, medical history, and surveillance over a median of 6.4 years.
- Cox proportional hazard models used to calculate hazard ratios (HRs) adjusted for confounding factors.
Main Results:
- A total of 296 AF incidents were recorded during the follow-up period.
- Heavy alcohol consumption (ethanol intake >69g/day) was associated with a significantly higher risk of AF.
- Compared to never-drinkers, heavy drinkers had a multivariable-adjusted HR of 2.90 (95% CI: 1.61-5.23) for incident AF.
Conclusions:
- Heavy alcohol consumption is a significant risk factor for developing atrial fibrillation.
- Findings underscore the need for public health awareness regarding heavy drinking and cardiovascular health, particularly AF.
Background:
Evidence regarding the relationship between different levels of alcohol consumption and the risk of atrial fibrillation (AF) is currently limited in Asian populations.
Methods And Results:
Between 1991 and 1995, a total of 8,602 Japanese men and women aged 30-80 years took part in the first examination of the Circulatory Risk in Communities Study (CIRCS), a population-based cohort study in Japanese communities. An interviewer obtained detailed information on weekly alcohol intake. During the follow-up period, the incidence of AF was ascertained from annual ECG records, the subject's medical history of AF, and cardiovascular disease surveillance. The hazard ratios (HRs) of incident AF and the 95% confidence intervals (CIs) relative to the never-drinking group were calculated with adjustment for potential confounding factors by using the Cox proportional hazard model. During a median follow-up period of 6.4 years, 296 incidents of AF occurred. A higher incidence of AF was observed among participants with an ethanol intake >69g/day, compared with never-drinkers. Compared with the never-drinkers, the multivariable-adjusted HRs (CIs) of past, light (<23g/day), light-moderate (23-46g/day), moderate (46-69g/day), and heavy (>69g/day) drinkers were 1.30 (0.68-2.49), 0.89 (0.60-1.32), 1.19 (0.73-1.95), 1.36 (0.79-2.35), and 2.90 (1.61-5.23), respectively.
Conclusions:
Heavy alcohol consumption is associated with a higher risk of AF.
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