Jove
Visualize
Contact Us

Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

2.8K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.8K
Teeth01:15

Teeth

2.2K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
2.2K
Assessment of the Mouth01:26

Assessment of the Mouth

1.6K
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.6K
The Oral Microbiota01:27

The Oral Microbiota

90
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
90
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents01:24

Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents

2.3K
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
2.3K
Handwashing II: Pre-procedure and Initial Procedure Steps01:19

Handwashing II: Pre-procedure and Initial Procedure Steps

1.5K
The pre-procedure steps of handwashing include removing jewelry and rolling up sleeves. However, many organizations allow staff to wear wedding rings.
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury.  The nails must be short and clean, without nail...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protocols for minimizing artifacts in estimating dental fluoride uptake from F-varnishes.

BMC research notes·2026
Same author

Laboratory evaluation of the erosive potential of fluoride-free mouthwashes using a dental erosion simulation model.

American journal of dentistry·2026
Same author

Erosion Potential of Commercial Fluoride-Free Mouthwashes on Dental Hard Tissues.

International journal of dental hygiene·2026
Same author

Comparative pharmacokinetics of fluoride secretion by major and labial minor salivary glands after oral fluoride intake.

Archives of oral biology·2025
Same author

Validation of an in vitro model to estimate the amount of fluoride released from toothpaste during toothbrushing.

Brazilian dental journal·2025
Same author

Increasing Global Trends in Early Childhood Caries Prevalence over the Last Decade: Global Burden of Disease Study 2021.

Caries research·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 2, 2026

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
03:37

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

Published on: June 6, 2025

645

Evidence-based recommendation on toothpaste use.

Jaime Aparecido Cury1, Livia Maria Andalo Tenuta1

  • 1Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.

Brazilian Oral Research
|February 21, 2014
PubMed
Summary

Fluoride toothpaste effectively reduces cavities in children and adults when used twice daily at a minimum of 1000 ppm F. Concerns about dental fluorosis from toothpaste ingestion in children are often overstated.

Area of Science:

  • Dentistry
  • Public Health
  • Preventive Medicine

Background:

  • Toothpaste serves as a delivery system for oral health-enhancing agents.
  • Recommendations for toothpaste ingredients should be evidence-based, not opinion-driven.
  • Fluoride is a key therapeutic agent in toothpaste for caries control.

Purpose of the Study:

  • To evaluate the scientific evidence supporting the use of fluoride toothpaste for dental caries prevention.
  • To assess the risks and benefits of fluoride toothpaste, including dental fluorosis concerns.
  • To review the efficacy of other therapeutic agents in toothpaste.

Main Methods:

  • Systematic review of scientific literature on fluoride toothpaste efficacy and safety.
  • Analysis of evidence regarding caries reduction and dental fluorosis risk.

More Related Videos

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
08:20

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

5.7K
Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
07:33

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

13.2K

Related Experiment Videos

Last Updated: May 2, 2026

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry
03:37

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

Published on: June 6, 2025

645
Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
08:20

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

5.7K
Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
07:33

Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs

Published on: July 6, 2015

13.2K
  • Evaluation of studies on other active ingredients like triclosan/copolymer and stannous fluoride.
  • Main Results:

    • Strong evidence supports fluoride toothpaste (≥1000 ppm F, ≥2 times/day) for caries reduction in all age groups.
    • The risk of dental fluorosis from toothpaste ingestion in children is likely overestimated.
    • Triclosan/copolymer and stannous fluoride show evidence of reducing biofilm, gingivitis, and other oral health issues.

    Conclusions:

    • Fluoride toothpaste is a highly effective and safe method for preventing dental caries.
    • Current recommendations regarding fluoride toothpaste use and fluorosis risk require re-evaluation based on scientific evidence.
    • Other therapeutic agents in toothpaste, such as triclosan/copolymer and stannous fluoride, offer additional oral health benefits.