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Osteoclasts in Bone Remodeling

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...

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Related Experiment Video

Updated: May 2, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

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Response to two recent BMJ papers on mortality after hip replacement: comparative modelling study

Ngianga-Bakwin Kandala¹, Martin Connock, Ruth Pulikottil-Jacob

¹Warwick Evidence, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.

BMJ (Clinical Research Ed.)

|February 21, 2014

Summary

No abstract available in PubMed .

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