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Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
Olfactory function after mild head injury in children
Valentin A Schriever1, Friederike Studt, Martin Smitka
1Smell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany. thummel@mail.zih.tu-dresden.de.
Insights
Mild head trauma in children can impact olfactory function, specifically odor detection thresholds. However, significant long-term olfactory impairment or loss is unlikely after such injuries.
Area of Science:
- Neurology
- Otolaryngology
- Pediatrics
Background:
- Olfactory impairment is associated with head injury.
- Olfactory function testing may indicate frontal brain damage after trauma.
Purpose of the Study:
- To assess the impact of mild head trauma on children's olfactory function.
- To track olfactory function changes for up to one year post-trauma.
Main Methods:
- 114 children with mild head trauma (Glasgow Coma Scale) were tested three times over one year.
- Olfactory function was compared to age-matched healthy controls.
- Tests included odor threshold and suprathreshold assessments.
Main Results:
- Children with mild head trauma showed significantly lower odor thresholds than controls, though still within normal limits.
- No significant differences were observed in suprathreshold testing between groups.
- Olfactory threshold and discrimination scores did not change significantly over the one-year study period.
Conclusions:
- Mild head trauma affects children's olfactory function, particularly odor detection.
- Significant long-term olfactory deficits like hyposmia or anosmia are improbable following mild head trauma in children.
Abstract:
Olfactory impairment has been shown to be linked to head injury. In addition, it is believed that measurement of olfactory function after head trauma represents a sensitive tool for measuring frontal brain damage. Aim of the study was to evaluate the effect of mild head trauma in children on olfactory function over a time period of up to 1 year after head trauma. The olfactory function of 114 children who suffered mild head trauma according to the Glasgow Coma Scale was assessed 3 times with an interval of 4 months. In addition, healthy, age-matched controls were tested for comparison of olfactory function. Patients scored significantly lower on the odor threshold test compared to the control group-but still within normal range. Between the 2 groups, no difference was found for suprathreshold testing. Neither olfactory threshold scores nor olfactory discrimination scores changed significantly over the study period of 1 year. This data prove an impact of mild head trauma on olfactory function of children. It seems unlikely that children who suffered mild head trauma will become hyposmic or anosmic.
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