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Updated: May 2, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
Feasibility of nephron-sparing surgery in giant oncocytoma
Albert El Hajj1, Ruban Thanigasalam2, Isabelle Boulay3
1Saint Joseph Hospital Trust, Department of Urology, Paris, France; ; American University of Beirut Medical Center, Division of Urology, Beirut, Lebanon.
Abstract:
Oncocytomas represent 3 to 7% of renal masses and behave as benign tumours. Nephron-sparing procedures are preferred for biopsy confirmed lesions; however, giant oncocytomas have been generally treated by radical nephrectomy. We report the first case of partial nephrectomy in a 45-year-old man who presented with a 20-cm oncocytoma. At the 1 year follow-up, he had a normal functioning kidney. Despite the difficulty of this procedure, partial nephrectomy for very large benign tumours can be considered in appropriately selected young patients.

