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Updated: May 2, 2026

Population and Single-Cell Analysis of Antibiotic Persistence in Escherichia coli
Published on: March 24, 2023
Differences in antibiotic use and knowledge between adolescent and adult mothers in Ecuador
Arturo Quizhpe P1, Martyna Gassowski2, Lorena Encalada T3
1International Center for Health Systems Research and Education, Radboud University Nijmegen Medical Centre, 500 HB, Nijmegen, Netherlands ; Faculty of Medical Sciences, University of Cuenca, Cuenca, EC010107, Ecuador.
Insights
Adolescent mothers show lower adherence to antibiotic treatment and less knowledge about antibiotic risks and resistance compared to adult mothers. Understanding these differences is key for effective interventions in Ecuador.
Area of Science:
- Public Health
- Pediatrics
- Infectious Diseases
Background:
- Antibiotic resistance is a growing global health concern.
- Understanding maternal knowledge and practices regarding antibiotic use is crucial for child health.
- Adolescent mothers may have unique challenges influencing their health-related decisions.
Purpose of the Study:
- To compare antibiotic use and knowledge between adolescent and adult mothers of children under five in Ecuador.
- To identify disparities in understanding antibiotic risks and resistance.
- To inform targeted public health interventions.
Main Methods:
- Cross-sectional study involving 777 mothers and their children under five with upper respiratory tract infections.
- Data collected via interviews using a structured questionnaire.
- Assessed knowledge of antibiotic treatment, risks, and resistance, alongside adherence.
Main Results:
- Adolescent mothers (15.8%) differed significantly from adult mothers (84.1%) in socio-economic factors.
- Adolescent mothers reported lower adherence (75.4% vs. 83.5%) and less knowledge about antibiotic risks (15.0% vs. 28.5%) and resistance (19.8% vs. 29.3%).
- Significant differences (p ≤ 0.05) were observed in all assessed areas.
Conclusions:
- Significant disparities exist in antibiotic knowledge and adherence between adolescent and adult mothers.
- Socio-economic factors may contribute to these differences.
- Tailored interventions are necessary to improve antibiotic stewardship among adolescent mothers.
Objectives:
To investigate the differences in antibiotic use and knowledge between adolescent and adult mothers of children under the age of 5 years in Ecuador.
Methods:
A cross sectional study was performed in four health centers and hospitals. Mothers of children under five years, seeking medical attention their child's upper respiratory tract infection (URI), were included. The data was collected through interviews, using a structured questionnaire. The questionnaire covered the topics knowledge of antibiotic treatment, risk and resistance.
Results:
777 mothers were included in the study, of which 15.8% were adolescent and 84.1% adult mothers. There were significant differences in the social and economic characteristics of the mothers (p ≤ 0.05), with adolescent mothers being more likely to have an incomplete high school education and lack of basic services in their home. Significant differences between these groups were found in adherence to treatment, knowledge about risks associated with antibiotic use, and having heard of antibiotic resistance. Among the adult mothers, 83.5% reported correct adherence, 28.5% were knowledgeable about risks associated with antibiotic use, and 29.3% had heard of antibiotic resistance. Among the adolescent mothers, these numbers were 75.4%, 15.0%, and 19.8%, respectively.
Conclusions:
To develop successful interventions, it is crucial to understand the factors causing differences in antibiotic use and knowledge between mothers.
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