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Paliperidone-associated motor tics.

Ming-Han Hsieh1, Nan-Ying Chiu2

  • 1Department of Psychiatry, Lutong Christian Hospital, Lukang Township, Changhua County, Taiwan.

General Hospital Psychiatry
|February 22, 2014
PubMed
Summary
This summary is machine-generated.

Paliperidone, an antipsychotic medication, can cause motor tics, such as eye blinking, in patients with schizophrenia. High doses of paliperidone may increase the risk of developing these tic-like symptoms.

Keywords:
Atypical antipsychoticsMotor ticsPaliperidone

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Area of Science:

  • Psychiatry
  • Clinical Pharmacology

Background:

  • Paliperidone is a widely used second-generation antipsychotic for treating schizophrenia.
  • Understanding its side effect profile is crucial for patient management.

Observation:

  • A case report details a 30-year-old male diagnosed with schizophrenia.
  • The patient developed motor tics, specifically eye blinking, during paliperidone treatment.

Findings:

  • The onset of motor tics was associated with paliperidone administration, reaching a daily dosage of 15 mg.
  • This suggests a potential link between paliperidone and the development of tic disorders.

Implications:

  • Clinicians should be vigilant for tic-like symptoms, ranging from simple eye blinking to Tourette-like syndrome, in patients treated with paliperidone.
  • Dose-dependent effects may be a factor, warranting careful titration and monitoring, especially at higher paliperidone doses.