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Ag-stained nucleolus organizer regions (Ag-NORs): expression in lymphocytes of patients with endometrial carcinoma

N Carlo Stella1, F Corrado, O Triolo

  • 1Department of Gynaecology, University of Messina, Italy.

European Journal of Gynaecological Oncology
|January 1, 1988
PubMed

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The nucleolus is the most prominent substructure of the nucleus. When it was first discovered, it was considered to be an isolated organelle that forms fibrils and granules. In 1931, the relationship between the nucleolus and chromosomes was first described by Heitz. He observed that the appearance and size of nucleolus varies depending on the stage of the cell cycle. He also noticed constricted regions on different chromosomes clustered together at definite cell cycle stages. These regions,...