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Paediatric drug development: the impact of evolving regulations

M A Turner1, M Catapano2, S Hirschfeld3

  • 1University of Liverpool, Department of Women's and Children's Health, Institute of Translational Medicine, Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool L8 7SS, UK.

Advanced Drug Delivery Reviews
|February 22, 2014
PubMed
Summary

Developing medicines for children requires significant effort within existing regulatory frameworks. This review examines paediatric drug development progress and outlines future directions for optimizing children's medicine accessibility.

Keywords:
Children's medicineExtrapolationPharmaceutical developmentPharmacodynamicsPharmacokineticsRegulatory frameworkRisk benefit ratio

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