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Updated: May 2, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
[Fever in returning travelers]
1ifi - Institut für Interdisziplinäre Medizin, Lohmühlenstr. 5, 20099, Hamburg, Deutschland, burchard@ifi-medizin.de.
Abstract:
Travel-related illness is most often due to gastrointestinal, febrile, and dermatologic diseases. Fever in a returned traveler demands prompt attention because it may be a manifestation of an infection that could be rapidly progressive and lethal. The approach to the febrile patient should be stepwise and consider travel and exposure history. Malaria is the most common cause of fever in patients returning from Sub-Saharan Africa, whereas dengue is more frequent in travelers from other tropical and subtropical areas. Other serious diseases are typhoid and paratyphoid fever, amebic liver abscess, visceral leishmaniasis, leptospirosis and-rarely-viral hemorrhagic fevers.
Insights
Fever in returned travelers requires immediate medical evaluation due to potentially severe infections. Key diagnoses include malaria, dengue, and typhoid fever, necessitating a travel history-informed approach.
Area of Science:
- Infectious Diseases
- Tropical Medicine
- Travel Medicine
Context:
- Travelers frequently experience gastrointestinal, febrile, and dermatologic illnesses.
- Fever in returned travelers can indicate rapidly progressive and life-threatening infections.
- A systematic approach considering travel history is crucial for diagnosis.
Purpose:
- To outline the common causes of fever in returned travelers.
- To emphasize the urgency of evaluating febrile patients with a relevant travel history.
- To highlight differential diagnoses including malaria, dengue, typhoid, and other serious tropical diseases.
Summary:
- Fever in individuals returning from travel necessitates prompt medical assessment.
- Malaria is prevalent in Sub-Saharan Africa, while dengue is common in other tropical regions.
- Other significant concerns include typhoid fever, amebic liver abscess, visceral leishmaniasis, leptospirosis, and viral hemorrhagic fevers.
Impact:
- Facilitates timely diagnosis and treatment of potentially fatal travel-related infections.
- Improves clinical decision-making for healthcare providers managing febrile travelers.
- Enhances awareness of the spectrum of infectious diseases encountered in global travel.
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