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Clinical Imaging of Microwave Mammography
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[Molecular breast imaging. An update].

K Pinker1, T H Helbich, H Magometschnigg

  • 1Abteilung für Molekulare Bildgebung, Universitätsklinik für Radiologie und Nuklearmedizin, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich.

Der Radiologe
|February 22, 2014
PubMed
Summary
This summary is machine-generated.

Molecular imaging advances breast cancer detection and characterization. New techniques promise improved tumor assessment, staging, and treatment monitoring by visualizing molecular processes.

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Area of Science:

  • Molecular imaging in oncology
  • Biomedical imaging techniques
  • Breast cancer research

Context:

  • Molecular imaging visualizes cellular and molecular processes in vivo.
  • Established techniques include multiparametric MRI, PET, and BSGI.
  • Breast imaging has increasingly adopted molecular imaging modalities.

Purpose:

  • To review current and emerging molecular imaging techniques for breast tumors.
  • To highlight the potential of molecular imaging in cancer detection and management.
  • To explore advancements in visualizing metabolic and molecular pathways in breast cancer.

Summary:

  • Current molecular imaging in breast cancer utilizes techniques like dynamic contrast-enhanced MRI (DCE-MRI), diffusion-weighted imaging (DWI), proton MR spectroscopy ((1)H-MRSI), breast-specific gamma imaging (BSGI), and positron emission tomography (PET).
  • Novel methods such as sodium imaging ((23)Na-MRI), phosphorus spectroscopy ((31)P-MRSI), and hyperpolarized MRI are under investigation.
  • These techniques allow for multiparametric assessment, including combinations like PET-CT and PET-MRI.

Impact:

  • Future molecular imaging of breast tumors will enable simultaneous assessment of multiple cancer-related processes.
  • This will lead to improved detection, characterization, and staging of breast cancer.
  • Enhanced monitoring of treatment response is anticipated, optimizing patient care.