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Flow Sheet01:17

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
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A flowchart for selecting an ointment base.

Jeannine M Conway1, Michael C Brown2

  • 1College of Pharmacy, University of Minnesota, Minneapolis, Minnesota.

American Journal of Pharmaceutical Education
|February 22, 2014
PubMed
Summary
This summary is machine-generated.

A flowchart significantly improved students' ability to select appropriate ointment bases in laboratory settings. This tool enhanced practical skills without increasing calculation, procedure, or labeling errors.

Keywords:
compoundingdecision-making flowchartnonsterile compoundingointment

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Area of Science:

  • Pharmaceutical Sciences
  • Pharmacy Education

Background:

  • Selecting appropriate ointment bases is a crucial skill for pharmacy students.
  • Traditional teaching methods may not fully equip students with practical decision-making abilities for base selection.

Purpose of the Study:

  • To enhance pharmacy students' competency in selecting suitable ointment bases.
  • To evaluate the effectiveness of a flowchart-designed educational tool in improving practical skills.

Main Methods:

  • A flowchart was developed to guide students in choosing the correct ointment base.
  • Students utilized the flowchart during both dry and wet laboratory sessions throughout a semester.
  • Student performance was assessed via a practical examination requiring ointment base and levigating agent selection.

Main Results:

  • Student success in selecting the correct ointment base increased significantly from 51/101 (pre-flowchart) to 169/212 (post-flowchart) (p<0.001).
  • No significant differences were observed in calculation, procedure, or labeling errors after flowchart implementation.
  • The flowchart proved effective in improving accuracy in base selection within a dry laboratory context.

Conclusions:

  • Implementing a flowchart is an effective strategy for improving students' skills in selecting appropriate ointment bases.
  • The flowchart enhances practical application of knowledge in pharmaceutical compounding.
  • This educational intervention offers a valuable tool for pharmacy curriculum development.