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Stem Cell Therapy for Tissue Regeneration

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Updated: May 2, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

From stem to roots: Tissue engineering in endodontics.

Rita Chandki¹, M Kala², Priyank Banthia³

¹M.D.S., Post graduate student. Department of conservative dentistry and Endodontics. Govt.Dental college and Research Institute, Bangalore, India.

Journal of Clinical and Experimental Dentistry

|February 22, 2014

Summary

This summary is machine-generated.

Regenerative endodontics uses tissue engineering to rebuild the tooth's dentin-pulp complex. This approach aims to restore tooth structure and function using patient-derived cells and scaffolds.

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Use of Trowell-Type Organ Culture to Study Regulation of Dental Stem Cells

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Published on: July 8, 2021

Area of Science:

Biomaterials Science
Regenerative Medicine
Dental Research

Background:

The dentin-pulp complex is vital for tooth vitality.
Tooth loss due to various factors significantly impacts oral function, aesthetics, and quality of life.
Current treatments for tooth loss have limitations in fully restoring natural tooth structure and function.

Purpose of the Study:

To review the concept of tissue engineering in endodontics.
To explore the application of tissue engineering for regenerating the pulp-dentin complex.
To provide insight into emerging developmental approaches in regenerative endodontics.

Main Methods:

Literature review of tissue engineering principles and applications in endodontics.
Analysis of studies focusing on stem cells, scaffolds, and growth factors for pulp-dentin regeneration.
Examination of technological advancements facilitating regenerative endodontic procedures.

Main Results:

Tissue engineering offers a biological approach to restore tooth structure.
Patient-specific cells and advanced scaffolds are key components for regenerating dental tissues.
Precise regulation of regenerative events is crucial for achieving desired tooth size and shape.

Conclusions:

Regenerative endodontics represents a promising frontier in dentistry.
Tissue engineering holds the potential to create 'test tube teeth' by regenerating the pulp-dentin complex.
Further technological development is essential for the clinical success of regenerative endodontic procedures.