Related Experiment Video
Updated: May 2, 2026

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Escherichia coli bacteraemia in adults: age-related differences in clinical and bacteriological characteristics, and
C Roubaud Baudron1, X Panhard2, O Clermont2
1Pôle de Gérontologie Clinique, CHU Hôpitaux de Bordeaux,F-33000 Bordeaux,France.
Abstract:
To explore the specificities of Escherichia coli bacteraemia in the elderly, the demographic, clinical and bacteriological characteristics and in-hospital mortality rate of 'young' (18-64 years, n = 395), 'old' (65-79 years, n = 372) and 'very old' (⩾80 years, n = 284) adult patients of the multicentre COLIBAFI cohort study were compared. Clinical and bacteriological risk factors for death were jointly identified by logistic regression and multivariate analysis within each group. 'Young' and 'old' patients had more comorbidities than 'very old' patients (comorbidity score: 1·5 ± 1·3 and 1·6 ± 1·2 vs. 1·2 ± 1·2, respectively; P < 0·001), and were more frequently nosocomially infected (22·3% and 23·8% vs. 8·8%, respectively; P < 0·001). 'Old' patients had the poorest prognosis (death rate: 16·4% vs.10·4% for 'young' and 12·0% for 'very old' patients, respectively; P = 0·039). Risk factors for death were age group-specific, suggesting a host-pathogen relationship evolving with age.
Related Concept Videos
Bacterial Gastroenteritis
Microbiota of the Urogenital Tract
Development of Human Microbiota
Bacterial Meningitis I: Introduction
Urinary Tract Infection II: Pathophysiology
Clinical Significance of Antibiotic Resistance

