Attention and executive functions in children with epilepsy: what, why, and what to do
William S MacAllister1, Marsha Vasserman, Joshua Rosenthal
1a Comprehensive Epilepsy Center, New York University , New York , New York.
Insights
Children with epilepsy often experience attention and executive function deficits. This review covers their neurological basis, impact in childhood epilepsy, and treatment strategies.
Area of Science:
- Neuroscience
- Pediatric Neurology
- Cognitive Psychology
Background:
- Attention and executive functions are crucial cognitive skills frequently impaired in pediatric neurological conditions.
- Epilepsy syndromes in childhood are consistently associated with executive dysfunction.
- Understanding these deficits is vital for effective management.
Purpose of the Study:
- To review the current knowledge on attention and executive functions, including their neurological underpinnings.
- To discuss general cognitive function and specific attention/executive function impairments in childhood epilepsy.
- To explore treatment considerations and future research directions for these deficits.
Main Methods:
- Literature review and synthesis of existing research.
- Focus on neurological basis of attention and executive functions.
- Analysis of cognitive function in childhood epilepsy.
Main Results:
- Attention and executive function deficits are common in childhood neurological disorders, particularly epilepsy.
- Specific patterns of executive dysfunction are observed across childhood epilepsy syndromes.
- Neurological underpinnings of these cognitive skills are complex and varied.
Conclusions:
- Children with epilepsy frequently exhibit attention and executive function impairments.
- Targeted interventions are necessary to address these cognitive deficits.
- Further research is needed to optimize treatment and improve outcomes for affected children.
Abstract:
Attention and executive function deficits are a common sequelae of many neurological conditions of childhood. Those with epilepsy frequently show such deficits, as executive dysfunction is common in all epilepsy syndromes of childhood. The purpose of this article is to review what is known about attention and executive functions, including the neurological underpinnings of these skills. Then, general cognitive function and dysfunction in childhood epilepsy is discussed with a special focus on attention and executive function impairment. Finally, treatment considerations for children and adolescents with these deficits are reviewed and future directions are discussed.
More Related Videos
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types
Seizures l: Introduction
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Antiepileptic Drugs: Glutamate Antagonists


