Skin as an indicator for sexually transmitted infections
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Updated: May 2, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
1STI Outpatient Clinic, Cluster of Infectious diseases, Public Health Service Amsterdam, Amsterdam, The Netherlands; Department of Dermatology, Academic Medical Center, Post Office Box 22700, 1100 DE, University of Amsterdam, Amsterdam, The Netherlands; Centre for Infection and Immunity Amsterdam (CINIMA) Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands; Centre for Infectious Diseases Control; National Institute for Public Health and the Environment (CIb/RIVM), Bilthoven, The Netherlands.
Abstract:
Cutaneous signs and skin conditions associated with sexually transmitted infections (STIs) are discussed. Syphilis, condyloma acuminata, and scabies are well-known STIs with cutaneous manifestations. Chlamydia and gonorrhea can also cause specific muco-cutaneous signs and symptoms. HIV often manifests itself through skin conditions. Dermatologists are pivotal in the timely diagnosis of HIV infection and play an important role in the disease prognosis and ongoing transmission. Anal intra-epithelial neoplasia (AIN), an HPV related precursor of anal carcinoma affecting HIV positive men, is a relatively new condition that many dermatologists will face in the future. STIs should be involved in the differential diagnosis when dermatologists are confronted with anogenital dermatoses, especially in patients with an increased risk for STIs.
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