Assessment of liver fat in an obese patient population using noncontrast CT fat percent index
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Ali F Jon1, Ahmad R Cheema1, Atif N Khan1
1Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Objective:
To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S).
Methods:
Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU.
Results:
There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05).
Conclusion:
Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
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