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Mast cells and IgE-mediated release of histamine and arachidonate metabolites from human kidney
E S Assem1, N A Abdullah, A G Cowie
1Department of Pharmacology, University College London, UK.
Abstract:
We report a pilot study of mast cells and IgE-mediated release of histamine, leukotrienes and thromboxanes from human kidney. The results together with previous findings in the guinea-pig and rat suggest that mast cells and IgE may play an important role in kidney disease.