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Updated: May 2, 2026
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
20.6K
Non-invasive anesthesia for children undergoing proton radiation therapy
Pascal Owusu-Agyemang1, David Grosshans2, Radha Arunkumar1
1Department of Anesthesiology & Perioperative Medicine, The University of Texas MD Anderson Cancer Center, United States.
Summary
Total Intravenous Anesthesia (TIVA) without daily endotracheal intubation is a safe and effective anesthetic option for pediatric proton therapy. This approach minimizes invasiveness while ensuring efficient patient care during radiation treatments.
Area of Science:
- Pediatric Anesthesiology
- Radiation Oncology
- Proton Therapy
Background:
- Proton therapy presents unique anesthetic challenges due to treatment setup and duration.
- Anesthesiologists require specific strategies for pediatric patients undergoing radiation.
Purpose of the Study:
- To detail the anesthesia practice for pediatric proton therapy patients.
- To report on the safety and complications of anesthesia during proton therapy.
Main Methods:
- Retrospective review of anesthetic records for patients aged 18 years or younger.
- Data collected from January 2006 to April 2013.
- Analysis of anesthesia duration and patient outcomes.
Main Results:
- 9328 anesthetics administered to 340 children (median age 3.6 years).
- Total Intravenous Anesthesia (TIVA) with spontaneous ventilation used in all patients.
- Low complication rate (0.05%), with no daily endotracheal intubations required.
Conclusions:
- TIVA without daily endotracheal intubation is a safe and efficient anesthetic method for pediatric proton therapy.
- This approach offers a less invasive option for pediatric patients.
- Freestanding proton therapy centers can successfully implement this anesthetic strategy.
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