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Lymphedema in a 7-year-old boy infected with Wuchereria bancrofti in Sierra Leone: a case report
Mackenzie Dome1, Rashid Ansumana2, Andrea L Covington3
1Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA.
Insights
A 7-year-old boy in Sierra Leone had congenital lymphedema and active filarial infection causing penile edema. This case highlights potential lymphatic drainage abnormalities in childhood lymphedema.
Area of Science:
- Pediatrics
- Infectious Diseases
- Genetics
Background:
- Congenital lymphedema is a rare condition affecting lymphatic system development.
- Filarial infections are endemic in many tropical regions, including Sierra Leone.
- Childhood lymphedema can stem from various congenital or acquired causes.
Observation:
- A 7-year-old boy presented with genital edema since 6 months of age.
- The patient had an active filarial infection.
- The edema was localized to the penile region.
Findings:
- The case suggests a possible congenital abnormality in lymphatic drainage contributing to genital edema.
- Active filarial infection may exacerbate or trigger lymphedema in susceptible individuals.
- Differential diagnoses for childhood lymphedema, such as Milroy's disease, were considered.
Implications:
- This case underscores the importance of considering both congenital and infectious etiologies in childhood lymphedema.
- Early diagnosis and management are crucial for preventing complications associated with lymphedema.
- Further research is needed to understand the interplay between filarial infections and congenital lymphatic abnormalities.
Abstract:
We present a case of congenital lymphedema in a 7-year-old boy in Sierra Leone with active filarial infection and penile edema. The genital edema with onset at 6 months of age may have been due to a congenital abnormality in lymphatic drainage. Other possible causes of childhood lymphedema, including Milroy's disease, are discussed.

