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Hormonal Regulation

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.

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Related Experiment Video

Updated: May 2, 2026

Measuring Skeletal Muscle Thermogenesis in Mice and Rats

Measuring Skeletal Muscle Thermogenesis in Mice and Rats

Published on: July 27, 2022

Mitohormesis.

Jeanho Yun¹, Toren Finkel²

¹Center for Molecular Medicine, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA; Department of Biochemistry and Mitochondria Hub Regulation Center, College of Medicine, Dong-A University, Busan 602-714, South Korea.

Cell Metabolism

|February 25, 2014

Summary

This summary is machine-generated.

Mitochondria, once seen as simple energy producers, are now understood to trigger cellular defense pathways. This stress response, called mitohormesis, enhances cell resilience and may explain aging.

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Measurements of Physiological Stress Responses in C. Elegans

Measurements of Physiological Stress Responses in C. Elegans

Published on: May 21, 2020

Area of Science:

Cell Biology
Molecular Biology
Aging Research

Background:

Mitochondria were historically viewed as independent organelles crucial for cellular energy production.
Emerging evidence highlights mitochondria's integration into cellular signaling networks.
Mitochondrial dysfunction is implicated in various age-related diseases.

Purpose of the Study:

To explore the concept of mitohormesis, a cellular response to mitochondrial stress.
To understand how mitochondrial stress impacts nuclear gene expression and cellular resilience.
To investigate the potential role of mitohormesis in aging and disease susceptibility.

Main Methods:

Investigated cellular signaling pathways activated by mitochondrial stress.
Analyzed changes in nuclear gene expression following mild mitochondrial perturbations.
Utilized various model organisms to study the mitohormesis phenomenon.

Main Results:

Mild mitochondrial stress rapidly activates cytosolic signaling pathways.
These pathways lead to alterations in nuclear gene expression.
Pre-conditioning cells to mild stress enhances their resistance to subsequent challenges.

Conclusions:

Mitochondria are integral components of cellular signaling, not just energy producers.
The mitohormesis response confers cellular resilience.
Understanding mitohormesis may offer insights into aging and disease.