Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physiological hypnic myoclonus.

P Montagna1, R Liguori, M Zucconi

  • 1Institute of Clinical Neurology, University of Bologna, Italy.

Electroencephalography and Clinical Neurophysiology
|August 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Women and multiple sclerosis: From gender medicine to precision medicine.

Multiple sclerosis and related disorders·2025
Same author

Hypogammaglobulinemia and severe infections in Multiple Sclerosis patients on anti-CD20 agents: A multicentre study.

Multiple sclerosis and related disorders·2024
Same author

Comparative effectiveness and cost-effectiveness of natalizumab and fingolimod in rapidly evolving severe relapsing-remitting multiple sclerosis in the United Kingdom.

Journal of medical economics·2023
Same author

Do patients' and referral centers' characteristics influence multiple sclerosis phenotypes? Results from the Italian multiple sclerosis and related disorders register.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2022
Same author

Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis.

BMC medical research methodology·2022
Same author

Dimethyl fumarate-induced lymphocyte count drop is related to clinical effectiveness in relapsing-remitting multiple sclerosis.

European journal of neurology·2020
Same journal

Coming to terms with brain waves.

Electroencephalography and clinical neurophysiology·2014
Same journal

Habituation of lower leg stretch responses in Parkinson's disease.

Electroencephalography and clinical neurophysiology·2000
Same journal

Asymmetry of cortical excitability revealed by transcranial stimulation in a patient with focal motor epilepsy and cortical myoclonus.

Electroencephalography and clinical neurophysiology·2000
Same journal

Evoked isometric muscle contractions in myopathies: analysis of pathophysiological properties by different stimulus patterns.

Electroencephalography and clinical neurophysiology·2000
Same journal

Task-related coherence and task-related spectral power changes during sequential finger movements.

Electroencephalography and clinical neurophysiology·2000
Same journal

Electrophysiological studies in mild idiopathic carpal tunnel syndrome.

Electroencephalography and clinical neurophysiology·2000
See all related articles

Physiological hypnic myoclonus (PHM) occurs during wakefulness and sleep, increasing in REM sleep. This spontaneous motor activity may be better described by other terms than

Area of Science:

  • Neuroscience
  • Sleep Medicine
  • Physiology

Background:

  • Physiological hypnic myoclonus (PHM) is a common phenomenon during the transition to sleep.
  • Understanding the quantification and characteristics of PHM during different sleep stages is crucial for differentiating it from pathological conditions.

Purpose of the Study:

  • To quantify physiological hypnic myoclonus (PHM) during wakefulness and sleep stages in healthy individuals.
  • To analyze the changes in PHM activity across different sleep stages and in specific muscles.

Main Methods:

  • Electromyography (EMG) was used to record muscle activity in 7 normal subjects.
  • PHM was quantified during relaxed wakefulness, stage 1 sleep, and rapid eye movement (REM) sleep.

Main Results:

Related Experiment Videos

  • PHM was observed during relaxed wakefulness and showed a significant increase during stage 1 and REM sleep.
  • Some muscles, like the soleus, did not exhibit an increase in PHM during sleep.
  • PHM activity resembled fasciculation potentials or fragmentary myoclonus seen in NREM sleep.

Conclusions:

  • The study quantifies PHM, demonstrating its prevalence and increase during sleep, particularly REM sleep.
  • The findings suggest that current terminology ('hypnic' and 'myoclonus') may not accurately describe this physiological motor activity.
  • Further research may be needed to establish more appropriate terminology and classification for these spontaneous muscle events.