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Updated: May 2, 2026

Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Iodine nutritional status among neonates in the Solan district, Himachal Pradesh, India
Umesh Kapil1, Madhulika Kabra, Shyam Prakash
1Department of Human Nutrition, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India, umeshkapil@gmail.com.
Insights
Iodine deficiency is a public health concern in Solan district, Himachal Pradesh, affecting 63.2% of neonates. This study assessed neonatal iodine status using thyroid-stimulating hormone (TSH) levels.
Area of Science:
- Endocrinology
- Public Health
- Neonatal Health
Background:
- Neonatal iodine nutrition status is crucial for development.
- Iodine deficiency (ID) can cause severe neurological and developmental issues.
- The World Health Organization (WHO) defines a population-level TSH above 5 mIU/L in over 3% of neonates as indicative of iodine deficiency.
Purpose of the Study:
- To assess the iodine nutrition status of neonates in Solan district, Himachal Pradesh.
- To determine the prevalence of iodine deficiency in the neonatal population of the region.
Main Methods:
- Screening of six hospitals/community health centers in Solan district.
- Selection of two hospitals based on operational feasibility.
- Collection and analysis of 683 neonatal umbilical cord blood samples for TSH levels.
Main Results:
- A high prevalence of elevated TSH levels was observed.
- 63.2% of neonates exhibited TSH levels exceeding 5 mIU/L.
- This indicates widespread iodine deficiency in the studied neonatal population.
Conclusions:
- Iodine deficiency represents a significant public health problem among neonates in Solan district, Himachal Pradesh.
- The findings highlight the urgent need for interventions to address iodine deficiency in this region.
Abstract:
Iodine nutrition status amongst neonates can be assessed by estimating thyroid stimulating hormone (TSH). According to WHO, if more than 3 % of the neonates have TSH levels of 5 mlU/l and more in a population, it indicates presence of iodine deficiency (ID). Iodine deficiency is an endemic health problem in Solan district, Himachal Pradesh (HP) state. ID leads to mental retardation, deaf mutism, squint, dwarfism, spastic diplegia, neurological defects and congenital anomalies. The aim is to determine iodine nutrition status of neonates of Solan district. In Solan district, six hospitals/community health centers providing obstetric services and conducting more than 100 deliveries per annum were identified and enlisted. Two hospitals were selected keeping in view of operational feasibility. A total of 683 umbilical cord blood samples of neonates were collected on filter paper and analyzed for TSH. It was found that 63.2 % of the neonates had TSH levels of more than 5 mlU/l indicating iodine deficiency in the Solan district. Iodine deficiency was a public health problem in Solan district, HP.
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