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Updated: May 2, 2026

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Published on: July 18, 2017
Nephrolithiasis by Corynebacterium urealyticum infection: literature review and case report
Laura Cappuccino1, Paolo Bottino, Adele Torricella
1University of Genoa and IRCCS AOU San Martino-IST, Genoa, Italy.
Introduction:
Alkaline-encrusted cystitis or pyelonephritis is a chronic inflammatory condition due to deposition of crystals usually caused by urea-splitting bacteria. Corynebacterium urealyticum (CU) is a gram-positive, urea-splitting and multi-antibiotic resistant bacillus with special tropism for the urinary tract and it is often associated with encrusted pyelocystitis.
Methods And Results:
Here we report the case of a 75-year-old Caucasian man with a prolonged history of renal stones who was admitted for gross hematuria associated with renal failure. A diagnosis of encrusted pyelocystitis due to CU infection was made and the patient was appropriately treated.
Conclusions:
At 6-month follow-up the patient was in good general conditions and asymptomatic. Signs of urinary tract infection or of renal calculosis were still detectable.
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Urinary Tract Infection I: Introduction
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Urinary Tract Calculi III: Medical Management

