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Visualizing Intracellular SNARE Trafficking by Fluorescence Lifetime Imaging Microscopy
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Parallel mechanisms for direct and indirect membrane protein trafficking by synucleins

Adam W Oaks1, Anita Sidhu1

  • 1Laboratory of Molecular Neurochemistry; Department of Biochemistry and Molecular & Cellular Biology; Georgetown University Medical Center; Washington, DC USA.

Communicative & Integrative Biology
|February 25, 2014
PubMed
Summary

Synuclein proteins, abundant in the brain, are implicated in cellular processes and monoamine transporter trafficking. New findings suggest synucleins influence dopamine transporter movement by affecting the endoplasmic reticulum and Golgi apparatus.

Keywords:
GolgiParkinson’s diseasedopamine uptakeendoplasmic reticulummood disorderssynucleintrafficking

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