Related Experiment Video

Updated: May 2, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

31.4K

Cardiac Function and Short-Term Outcome in Patients with Acute Ischemic Stroke: A Cross-Sectional Study

Tiffany L Mathias1, Karen C Albright1, Amelia K Boehme1

  • 1Stroke Program, Department of Neurology, Tulane University Hospital, New Orleans, LA 70112 (TLM, DM, AJG, EJ, SMS); Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (KCA, AKB); Health Services and Outcomes Research Center for Outcome and Effectiveness Research and Education (COERE) (KCA); Center of Excellence in Comparative Effectiveness Research for Eliminating Disparities (CERED) Minority Health & Health Disparities Research Center (MHRC) (KCA); Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35249 (TMB).

Journal of Cardiovascular Disease
|February 25, 2014
PubMed

Insights

Low left ventricular ejection fraction (LVEF) in ischemic stroke patients was not significantly linked to poorer short-term functional outcomes after accounting for other factors. Further research is needed to fully understand this relationship.

Area of Science:

  • Cardiology
  • Neurology
  • Medical Research

Background:

  • Limited research exists on the association between left ventricular ejection fraction (LVEF) and functional outcomes in ischemic stroke patients.
  • Understanding factors influencing stroke recovery is crucial for patient management.

Purpose of the Study:

  • To investigate if a reduced LVEF is associated with functional outcomes in patients following an ischemic stroke.
  • To identify potential predictors of functional recovery after ischemic stroke.

Main Methods:

  • A cross-sectional study analyzed 590 ischemic stroke patients.
  • Left ventricular ejection fraction (LVEF) was assessed via echocardiography and categorized into normal, moderately low, and severely low groups.
  • Statistical analyses included Chi-square, Wilcoxon rank sum, and logistic regression, adjusting for age, NIH Stroke Scale, and glucose levels.

Main Results:

  • 79.8% of patients had normal LVEF, 10.8% moderately low, and 9.3% severely low.
  • Initially, severely low LVEF appeared linked to poorer functional outcomes (26% vs. 40-45%, p=0.028).
  • This association was not statistically significant after adjusting for covariates (OR 0.6, 95% CI 0.3-1.3, p=0.216).

Conclusions:

  • Low LVEF was not found to be an independent predictor of short-term functional outcomes in ischemic stroke patients.
  • The study highlights the complexity of factors influencing stroke recovery.
  • Further investigation into cardiac function and stroke outcomes is warranted.

More Related Videos

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

14.4K
Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs14:35

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Published on: April 17, 2021

9.0K

Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
54
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
495
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
522
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
1.2K