Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Growth of Cartilage and Bone Tissue

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

Bone Remodeling and Repair

Bone Remodeling and Repair

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Feature representation for explainable CRISPR off-target prediction and base editing efficiency.

Frontiers in bioinformatics·2026

Same author

International Forum on Visceral Myopathy 2024: Advances in the Knowledge of the Disease.

Neurogastroenterology and motility·2026

Same author

Uncovering miRNA-Disease Associations Through Graph Based Neural Network Representations.

Biomedicines·2026

Same author

Correction: A multi-organ-on-chip to recapitulate the infiltration and the cytotoxic activity of circulating NK cells in 3D matrix-based tumor model.

Frontiers in bioengineering and biotechnology·2026

Same author

Skin-on-Chip and clinical evaluation of the soothing potential of a topical natural treatment for atopic-prone skin: An exploratory study.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026

Same author

Coupling Adoptive Cell Therapy with Boron Neutron Capture Therapy: Using Functional Tumor-Infiltrating Lymphocytes for Tumor Delivery of Boron Carbide Nanoparticles.

ACS nano·2025

Search research articles

Related Experiment Video

Updated: May 2, 2026

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Published on: July 14, 2023

Guidelines for managing data and processes in bone and cartilage tissue engineering.

Federica Viti, Silvia Scaglione, Alessandro Orro

BMC Bioinformatics

|February 26, 2014

Summary

This summary is machine-generated.

Standardized methods are crucial for bone and cartilage tissue engineering. This study introduces a conceptual framework and ontology to unify data and improve interpretation of regenerative medicine research.

More Related Videos

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Published on: April 14, 2026

Related Experiment Videos

Last Updated: May 2, 2026

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Published on: July 14, 2023

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering

Published on: April 25, 2013

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Establishment and Evaluation of a Sheep Model of Full-thickness Osteochondral Defect

Published on: April 14, 2026

Area of Science:

Biomaterials Science
Regenerative Medicine
Bioinformatics

Background:

Tissue engineering utilizes biomaterials to guide tissue regeneration, with numerous studies testing scaffold effectiveness.
Data integration and meta-analysis are increasingly important for analyzing and reusing experimental data in tissue engineering.
Standardization and ontologies are essential for a unified knowledge framework to annotate data and interpret results in regenerative medicine.

Purpose of the Study:

To design a conceptual framework for the bone and cartilage tissue engineering domain.
To establish guidelines for minimum information required in experimental studies.
To develop a Bone/Cartilage Tissue Engineering Ontology (BCTEO) for domain concept representation.

Main Methods:

Development of a conceptual framework for bone and cartilage tissue engineering.
Establishment of guidelines for minimum experimental data reporting.
Creation of the Bone/Cartilage Tissue Engineering Ontology (BCTEO).

Main Results:

A conceptual framework and guidelines for bone/cartilage tissue engineering studies have been designed.
The Bone/Cartilage Tissue Engineering Ontology (BCTEO) was developed, representing domain concepts.
The BCTEO focuses on cells, biomaterial composition, morphology, and physical characterization.

Conclusions:

The proposed framework and ontology represent a foundational effort to standardize knowledge in tissue engineering.
These instruments facilitate data integration across diverse semantic fields and data types within tissue engineering.
The developed tools aim to support the unambiguous interpretation of novel experimental results in regenerative medicine.