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Current and future directions in pediatric allergic rhinitis
Deborah Gentile1, Ashton Bartholow1, Erkka Valovirta2
1Division of Allergy, Asthma and Immunology, Department of Medicine, Allegheny General Hospital, Pittsburgh, Pa.
Insights
Pediatric allergic rhinitis (AR) is increasing and impacts children's quality of life. Current treatments include avoidance and medication, with newer therapies on the horizon.
Area of Science:
- Pediatric Allergy and Immunology
- Otolaryngology
- Respiratory Medicine
Background:
- Allergic rhinitis (AR) is a prevalent pediatric condition.
- It significantly impairs children's sleep, learning, performance, and overall quality of life.
- AR is linked to substantial comorbidities and complications.
Purpose of the Study:
- To provide an updated review of pediatric allergic rhinitis.
- Key areas covered include epidemiology, comorbidities, pathophysiology, current treatments, and future directions.
Main Methods:
- A comprehensive literature review was conducted.
- Information from various sources was synthesized to provide a current overview.
Main Results:
- The prevalence of pediatric AR is rising globally.
- This condition is associated with significant morbidity, comorbidities, and complications.
- Current management strategies focus on allergen avoidance, pharmacotherapy, and allergen-specific immunotherapy.
Conclusions:
- Future diagnostic advancements include microarrayed recombinant allergen testing.
- Emerging therapies such as sublingual immunotherapy and combination products will expand treatment options.
Background:
Allergic rhinitis (AR) is a common pediatric problem that significantly affects sleep, learning, performance, and quality of life. In addition, it is associated with significant comorbidities and complications.
Objective:
The aim was to provide an update on the epidemiology, comorbidities, pathophysiology, current treatment, and future direction of pediatric AR.
Methods:
Literature reviews in each of these areas were conducted, and the results were incorporated.
Results:
The prevalence of AR is increasing in the pediatric population and is associated with significant morbidity, comorbidities, and complications. The mainstay of current treatment strategies includes allergen avoidance, pharmacotherapy, and allergen specific immunotherapy.
Conclusions:
In the future, diagnosis will be improved by microarrayed recombinant allergen testing and therapy will be expanded to include emerging treatments such as sublingual immunotherapy and combination products.
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