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Updated: Aug 12, 2026
13:27
Generation of Human CD40-activated B cells
Published on: October 17, 2009
Expression of B220 antigen on an interleukin 4- and interleukin 5-producing T-cell line
Scandinavian Journal of Immunology
|July 1, 1988
Abstract:
The murine T-cell line 2.19, originally used for cloning of interleukin 4 (IL-4) and IL-5, was analysed for surface marker characteristics using monoclonal antibodies and a FACS-4 analyser and found to be positive for the B220 antigen. Thus, this lymphokine-producing cell with characteristic T-cell markers expresses an antigen earlier thought to be specific for B cells. With two-colour fluorescence it was found that a small fraction (2-4%) of Thy 1+ spleen cells from normal CBA mice were also positive for B220.
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