Related Experiment Video
Updated: May 2, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
Upper tract changes in patients with neurogenic bladder and sustained pressures >40 cm following bladder neck surgery
Warren Snodgrass1, Carlos Villaneuva1, Micah Jacobs1
1Pediatric Urology Section, UT Southwestern Medical Center, Dallas, TX, USA; Children's Medical Center, Dallas, TX, USA.
Objective:
We report new hydronephrosis or VUR (vesicoureteral reflux) in patients with end filling pressures >40 cm for at least 1 year after bladder neck surgery without augmentation for neurogenic incontinence.
Materials:
Consecutive children with neurogenic sphincteric incompetency had bladder neck surgery without augmentation. Postoperative renal sonography and fluoroscopic urodynamics were done at 6 months, 12 months, and then annually. Those with sustained end fill pressures >40 cm for ≥ 1 year were included as participants in the study.
Results:
Of 79 patients, 17 (22%) had end fill pressures >40 cm for at least 1 year despite anticholinergics, with follow-up a mean of 39 months. New hydronephrosis or VUR developed in six (35%). All new hydronephrosis resolved with medical treatment, as did two out of three new VUR cases. The other patient with VUR had successful Dx/HA (dextranomer hyaluronic acid) injection.
Conclusions:
Despite sustained pressures >40 cm, upper tract changes developed in only 35% of patients, and resolved with medical management or minimally invasive interventions. End pressures should not be used as an independent indication for augmentation.
Related Concept Videos
Aneurysm IV: Nursing Management
Increased Intracranial Pressure l: Introduction
Urinary Tract Calculi VI: Surgical Management
Imaging Studies VI: Voiding Cystourethrography and Cystography
Nursing Assessment of the Genitourinary System II: Inspection and Palpation
Urinary Tract Infection IV: Nursing Management

