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Updated: May 2, 2026

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Published on: March 30, 2015
A large pelvic soft tissue mass implied by subtle bone scan findings.
Jianmin Huang1, Sherwin Chan, Sabah Servase
1From the *Department of Nuclear Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China; and †Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Bone scintigraphy revealed unexpected urinary bladder and genital region abnormalities in an 18-year-old man undergoing chemotherapy for rhabdomyosarcoma. Further imaging confirmed a pelvic mass and edema, suggesting treatment complications.
Area of Science:
- Oncology
- Radiology
- Urology
Background:
- Alveolar rhabdomyosarcoma is a rare and aggressive soft tissue sarcoma.
- Bone scintigraphy is commonly used to monitor skeletal metastases and treatment response.
Observation:
- Bone scintigraphy demonstrated significant improvement in osseous metastases.
- Incidental findings included a vertically oriented urinary bladder and increased radiotracer uptake in the genital region.
Findings:
- Pelvic CT revealed a thickened bladder wall, an ill-defined pelvic mass, and extensive subcutaneous edema of the genitalia.
- These findings suggest potential genitourinary involvement or complications related to rhabdomyosarcoma treatment.
Implications:
- Highlights the importance of recognizing incidental findings on bone scintigraphy.
- Suggests potential need for enhanced genitourinary surveillance in patients with pelvic rhabdomyosarcoma.
- Underscores the utility of integrated imaging approaches for comprehensive patient assessment.
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