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T1 mapping in ischaemic heart disease.

Darach O h-Ici¹, Sarah Jeuthe², Nadya Al-Wakeel²

¹Department of Congenital Heart Disease and Pediatric Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, Berlin 13353, Germany Division of Imaging Sciences and Biomedical Engineering, St Thomas' Hospital, 4th Floor, Lambeth Wing, Westminster Bridge Road, London SE1 7EH, UK darachohici@gmail.com.

European Heart Journal. Cardiovascular Imaging

|February 26, 2014

Summary

Cardiac magnetic resonance T1 mapping, a robust clinical tool, offers precise myocardial characterization. This technique shows significant potential for diagnosing and treating ischemic heart disease, including myocardial infarction.

Area of Science:

Cardiovascular imaging
Biomedical engineering
Medical physics

Background:

Cardiac magnetic resonance (CMR) uniquely characterizes myocardium.
Proton relaxation times (T1, T2, T2*) reflect tissue composition and disease states.
T1 mapping research has primarily focused on cardiomyopathies.

Purpose of the Study:

To review the current research on myocardial T1 mapping.
To highlight the clinical potential of T1 mapping in ischemic heart disease.
To demonstrate T1 mapping's utility in diagnosing and treating myocardial infarction.

Main Methods:

Utilizing robust high-resolution myocardial T1 mapping.
Employing quantitative imaging techniques.
Performing simple, minimally subjective, and highly reproducible analyses.

Main Results:

T1 mapping has been historically used to characterize myocardial infarction.
High-resolution myocardial T1 mapping is now a clinical tool.
The technique is simple to perform and analyze, with high reproducibility.

Conclusions:

Myocardial T1 mapping is a valuable tool for ischemic heart disease.
The technique aids in the diagnosis and treatment of patients.
T1 mapping offers significant potential beyond cardiomyopathies for cardiovascular assessment.

Keywords:

ECV Ischaemic heart disease Myocardial infarction Myocardial ischaemia T1 Mapping

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