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Cryptococcal infection in non-HIV immunosuppressed patients - Three case reports in a nephrology setting
Pedro Ventura Aguiar1, Virgínia Lopes2, La Salete Martins1
1Nephrology Department - Oporto Hospital Centre, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
Abstract:
Cryptococcal infection has been increasing among immunosuppressed population. We report three cases of Cryptococcus neoformans infection in immunosuppressed patients - two renal transplanted and one with lupus nephritis. Early infection (<3months) was diagnosed in two - an allograft Cryptococcus infection and a central nervous system involvement. The third, a 10-year transplant vintage patient, presented with cryptococcal meningitis. Amphotericin B provided good clinical outcomes. We outline the importance of suspicion for cryptococcal infection in immunosuppressed patients.
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